GANIRELIX ACETATE 250mcg
(ANTAGON™)

Description:
Ganirelix Acetate is an injectable gonadotropin releasing hormone with specific antagonistic (blocking) activity. It is indicated for the inhibition of premature LH (leuteinizing hormone) surges in women undergoing controlled ovarian hyperstimulation. Ganirelix Acetate is available as a prefilled syringe containing 250mcg/0.5ml.

How It Works:
Ganirelix Acetate is an injectable medication administered subcutaneously. Antagon is administered once daily. It is initiated a few days after FSH (follicle stimulating hormone) therapy and should be continued until the day of HCG administration. Ganirelix Acetate works immediately by suppressing LH and FSH secretion. This allows for eggs to reach the level of development needed for fertilization.

Potential Side Effects:
Side effects may occur including: abdominal pain, headache, vaginal bleeding, nausea, and injection site reaction.

If you experience an allergic reaction: difficulty breathing; closing of the throat; swelling of the lips, tongue or face; or hives; seek emergency medical attention immediately. And if any time you experience: pain, warmth, redness, numbness, or tingling in an arm or leg; confusion, severe dizziness or severe headache, seek medical attention immediately.

PLEASE NOTE: If these or any other side effects occur, contact your physician.

Storage:
Ganirelix can be stored at room temperature.

Subcutaneous Administration of
GANIRELIX ACETATE (ANTAGON)

Cleanse your selected SUBCUTANEOUS injection site with an alcohol wipe and allow to dry. Remove cover from needle and invert the syringe so the needle is pointing upwards and tap the syringe to force any air bubbles to the top. Depress the plunger to expel the air.. While holding the syringe with your dominant hand between your thumb and finger (as you would a pencil), pinch the skin (with your other hand) at the site you have selected. With a quick, dart-like motion, insert the entire needle (up to the hub of the syringe) at a 90° or a 45° angle and depress the plunger slowly and carefully. After the injection is complete, quickly pull out the needle. If bleeding, apply pressure to the injection site with a sterile gauze pad. If discomfort occurs after your injection, you may gently massage the injection site to alleviate your discomfort. After injecting the medication dispose of the syringe into the Sharps waste container. It is unnecessary to recap the needle as this could cause injury.