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Repronex

Description:

Repronex (human menopausal gonadotropin, hMG) is used to stimulate the production of follicles/eggs in women who are unable to produce eggs for functional reasons rather than primary ovarian failure. It is also used for stimulating the development of multiple follicles as part of an assisted reproductive technology (ART) program. Each vial contains 75 IU (international units) of powdered medication to be mixed with diluent.

How It Works:

Repronex is administered by subcutaneous or intramuscular injection. It promotes the development and maturation of follicles in the ovaries. Repronex is a gonadotropin that contains a combination of follicle stimulating hormone (FSH) and luteinizing hormone (LH).

Potential Side Effects

Side effects that may occur include: mild to moderate ovarian enlargement, ovarian cysts, nausea, vomiting, diarrhea, abdominal cramping, abdominal pain, bloating, dizziness, breast tenderness, body rash, and injection site reactions (pain, rash, swelling, irritation). The risk of ovarian hyperstimulation syndrome (OHSS) should be discussed with your physician prior to treatment. Early warning signs include severe pelvic pain, nausea, vomiting, and weight gain.

If you experience an allergic reaction: difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives; seek emergency medical attention immediately. And if at any time you experience: pain, warmth, redness, numbness, or tingling in an arm or leg; confusion, severe dizziness or severe headache, seek emergency medical attention immediately.

PLEASE NOTE: If these or any other side effects occur, contact your physician.

Storage:

Repronex may be stored refrigerated or at room temperature 37-77ºF. Protect from light. Use immediately after reconstitution. Discard unused material.

Mixing Repronex

  • Pop off the plastic top of powdered medication and diluent (liquid).
  • Swab the top of each vial with an alcohol pad to prevent contamination.
  • Select a 3cc syringe with 1 1/2" needle for mixing.  Twist to secure needle.
  • Using your syringe, draw back 1cc of air into the syringe.
  • Firmly insert the needle through the rubber stopper into the vial of diluent . Invert, or turn upside down, the vial and syringe as one complete unit and depress the air into the vial in order to equalize the pressure, which will make withdrawal of the diluent easier. Once you depress the plunger of the air-filled syringe into the vial, make sure the tip of the needle is BELOW the liquid level and pull the plunger to withdraw 1cc of the diluent.
  • Slowly and cautiously deposit the diluent into the vial of powdered medication. Rotate the vial between your thumb and index finger until the solution is clear. Withdraw the newly mixed medication back into the syringe. Remove the syringe from the vial.
  • Invert the syringe so the needle is pointing upwards and tap the syringe to force any air bubbles to the top.  Depress the plunger to expel the air.

Mixing More Than One vial of Repronex

  • Inject the contents of the syringe (powdered medication mixed with diluent) directly into the next vial of powdered medication, slowly and cautiously. This will increase the dosage without increasing the liquid volume. Do not use more diluent for addition vials of Repronex. Again, rotate the vial between your thumb and index finger until the solution is clear.
  • Withdraw the newly mixed Repronex from the second via back into the syringe.
  • Invert the syringe so the needle is pointing upwards and tap the syringe to force any air bubbles to the top. Depress the plunger to expel the air.
  • Repeat until you have reached your prescribed vial dosage. Withdraw the medication mixture from the final vial into the syringe and prepare for your injection.

If you are now ready for your subcutaneous injection, recap and remove the mixing needle by twisting and replace it with the smaller subcutaneous injection needle (usually 1/2” needle). Proceed to injection instructions

If you are now ready for your intramuscular injection, recap and remove the mixing needle by twisting and replace it with the intramuscular injection needle (usually 1 1/2" needle). Proceed to injection instructions.

Injection Instructions

For more product details or more detailed injection information please see
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