CETROTIDE®

Cetrotide 0.25mg

Cetrotide 3mg
Cetrotide (cetrorelix) is a gonadotropin-releasing hormone with antagonistic (blocking) activity. Cetrotide is used to prevent premature ovulation/LH (luteinizing hormone) surge in women undergoing controlled ovarian stimulation. The Cetrotide 0.25mg is a daily dose given for a number of days to be determined by your physician. The Cetrotide 3mg (single dose) controls the LH surge for up to 4 days.

Description: A GnRH antagonist, which blocks GnRH receptors on the pituitary gonadotropin pathway. It induces a rapid, reversible suppression of gonadotropin secretion.The vials of Cetrotide contain 0.25mg and 3mg of powdered medication packaged with prefilled syringes of diluent.

How It Works: Cetrotide is an injectable medication administered subcutaneously. Cetrotide blocks the effect of the naturally occurring gonadotropin releasing hormone (GnRH). GnRH controls the release of LH that produces the release of an egg from the ovary. Cetrotide is given over a short period of time in the cycle when the LH surge can occur. Its blocking effect allows for eggs to reach the level of development needed for fertilization.

Potential Side Effects: Some women may experience headache, abdominal pain and nausea, and injection site reactions (redness, bruising, itching or swelling)

If you experience an allergic reaction: difficulty breathing; closing of your throat; swelling of your lips, tongue or face; or hives; seek emergency medical attention immediately.

PLEASE NOTE: If these or any other side effects occur, contact your physician.

Storage: Store 3mg Cetrotide at room temperature. Protect from light. • Cetrotide 0.25mg must be refrigerated.

Subcutaneous Administration of CETROTIDE

Pop off the plastic top of the vial of the Cetrotide.
Swab the top of the vial with an alcohol pad to prevent contamination.
Using the prefilled diluent syringe, slowly and cautiously deposit the diluent into the vial of powdered medication. Rotate the vial between your thumb and index finger until the solution is clear. Withdraw the newly mixed medication back into the syringe. Carefully recap and remove the mixing needle by twisting and replace it with a smaller subcutaneous injection needle provided.
Invert the syringe so the needle is pointing upwards and tap the syringe to force any air bubbles to the top. Depress the plunger to expel the air.
Cleanse your selected SUBCUTANEOUS injection site with an alcohol wipe and allow to dry.
While holding the syringe with your dominant hand between your thumb and finger (as you would a pencil), pinch the skin (with your other hand) at the site you have selected.
After the injection is complete, quickly pull out the needle. If bleeding, apply pressure to the injection site with a sterile gauze pad. If discomfort occurs after your injection, you may gently massage the injection site to alleviate your discomfort.
After injecting the medication, dispose of the syringe into the Sharps waste container. It is unnecessary to recap the needle as this could cause injury